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このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10119/4932
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| タイトル: | Enhanced Effects of Lithocholic Acid Incorporation into Liquid Crystalline Biopolymer Poly(Coumaric Acid) on Structural Ordering and Cell Adhesion |
| 著者: | Matsusaki, Michiya
Tran, Hang Thi
Kaneko, Tatsuo
Akashi, Mitsuru |
| 発行日: | 2005-11 |
| 出版者: | Elsevier |
| 誌名: | Biomaterials |
| 巻: | 26 |
| 号: | 32 |
| 開始ページ: | 6263 |
| 終了ページ: | 6270 |
| DOI: | 10.1016/j.biomaterials.2005.03.044 |
| 抄録: | A novel thermotropic liquid crystalline biocopolymer, poly{4-hydroxycinnamic acid (4HCA: coumaric acid)-co-lithocholic acid (LCA)}, was synthesized by a thermal polycondensation of 4HCA and LCA. When the LCA molar composition of P(4HCA-co-LCA)) was 0, 5, 7, 23, 27, and 45 mol%, the copolymers showed a nematic liquid-crystalline phase. The melting point of the copolymers was 120-250 oC depending on the LCA composition, and showed a maximum at 7 mol%. Wide angle X-ray diffraction (WAXD) analysis showed a typical diffraction pattern of a hexagonal arrangement for 0, 7, 23, and 27 mol% LCA molar composition, which were cooled from a nematic melt. The other polymers showed no distinct diffraction. In particular, the copolymer of 7 mol% LCA molar composition showed four distinct diffractions corresponding to spacings with a reciprocal ratio of 1, 3^<0.5>, 2, and 7^<0.5>, indicating the highest structural ordering of all copolymers prepared here. The results of the cell adhesion and static contact angle tests suggest that the 7 mol% LCA molar composition copolymer had the highest hydrophobicity and cell adhesion ability, which was easily controlled by altering in feed. We conclude that the structural ordering may have a significant correlation with cell adhesion activity. |
| Rights: | NOTICE: This is the author's version of a work accepted for publication by Elsevier. Michiya Matsusaki, Tran Hang Thi, Tatsuo Kaneko and Mitsuru Akashi, Biomaterials, 26(32), 2005, 6263-6270, http://dx.doi.org/10.1016/j.biomaterials.2005.03.044 |
| URI: | http://hdl.handle.net/10119/4932 |
| 資料タイプ: | author |
| 出現コレクション: | c10-1. 雑誌掲載論文 (Journal Articles)
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